TY - JOUR
T1 - Next-generation ingestible devices
T2 - sensing, locomotion and navigation
AU - Alsunaydih, Fahad N.
AU - Yuce, Mehmet R.
N1 - Publisher Copyright:
© 2021 Institute of Physics and Engineering in Medicine
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/5/11
Y1 - 2021/5/11
N2 - There is significant interest in exploring the human body’s internal activities and measuring important parameters to understand, treat and diagnose the digestive system environment and related diseases. Wireless capsule endoscopy (WCE) is widely used for gastrointestinal (GI) tract exploration due to its effectiveness as it provides no pain and is totally tolerated by the patient. Current ingestible sensing technology provides a valuable diagnostic tool to establish a platform for monitoring the physiological and biological activities inside the human body. It is also used for visualizing the GI tract to observe abnormalities by recording the internal cavity while moving. However, the capsule endoscopy is still passive, and there is no successful locomotion method to control its mobility through the whole GI tract. Drug delivery, localization of abnormalities, cost reduction and time consumption are improvements that can be gained from having active ingestible WCEs. In this article, the current technological developments of ingestible devices including sensing, locomotion and navigation are discussed and compared. The main features required to implement next-generation active WCEs are explored. The methods are evaluated in terms of the most important features such as safety, velocity, complexity of design, control, and power consumption.
AB - There is significant interest in exploring the human body’s internal activities and measuring important parameters to understand, treat and diagnose the digestive system environment and related diseases. Wireless capsule endoscopy (WCE) is widely used for gastrointestinal (GI) tract exploration due to its effectiveness as it provides no pain and is totally tolerated by the patient. Current ingestible sensing technology provides a valuable diagnostic tool to establish a platform for monitoring the physiological and biological activities inside the human body. It is also used for visualizing the GI tract to observe abnormalities by recording the internal cavity while moving. However, the capsule endoscopy is still passive, and there is no successful locomotion method to control its mobility through the whole GI tract. Drug delivery, localization of abnormalities, cost reduction and time consumption are improvements that can be gained from having active ingestible WCEs. In this article, the current technological developments of ingestible devices including sensing, locomotion and navigation are discussed and compared. The main features required to implement next-generation active WCEs are explored. The methods are evaluated in terms of the most important features such as safety, velocity, complexity of design, control, and power consumption.
KW - Bio-inspired mechanisms
KW - Capsule endoscopy locomotion
KW - Electromagnetic platform
KW - Gastrointestinal (GI) tract
KW - Ingestible sensors
KW - Swallowable devices
KW - Wireless capsule endoscopy (WCE)
UR - http://www.scopus.com/inward/record.url?scp=85106541527&partnerID=8YFLogxK
U2 - 10.1088/1361-6579/abedc0
DO - 10.1088/1361-6579/abedc0
M3 - Review Article
C2 - 33706294
AN - SCOPUS:85106541527
SN - 0967-3334
VL - 42
JO - Physiological Measurement
JF - Physiological Measurement
IS - 4
M1 - 04TR01
ER -