The autoantibodies characteristic of the disease react against mitochondrial enzymes essential to the function of all body cells, yet the disease is highly focused on only one tissue: the epithelial lining of intrahepatic bile ductules. The explanation may lie in tissue-specific cell- surface expression of a triggering antigen.
|Number of pages||8|
|Journal||Hospital Practice (Office Editon)|
|Publication status||Published - 1 Dec 1995|