Abstract
There are still a significant number of bacterial infections for which no vaccines are available and several of the existing vaccines are suboptimal. However, the science of genomics is providing new approaches, including reverse vaccinology, identifying new candidate antigens, and assessing potential vaccine coverage. These advances are stimulating a reappraisal of the field and new candidate vaccines are emerging.
| Original language | English |
|---|---|
| Title of host publication | The Vaccine Book: Second Edition |
| Publisher | Elsevier |
| Pages | 311-329 |
| Number of pages | 19 |
| ISBN (Print) | 9780128021743 |
| DOIs | |
| Publication status | Published - 11 Jul 2016 |
| Externally published | Yes |
Keywords
- Adjuvant
- Genomics
- Meningitis
- Oral
- Reverse vaccinology
Cite this
}
New Approaches for Needed Vaccines : Bacteria. / MacLennan, Calman A; Mutreja, Ankur; Dougan, Gordon.
The Vaccine Book: Second Edition. Elsevier, 2016. p. 311-329.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
TY - CHAP
T1 - New Approaches for Needed Vaccines
T2 - Bacteria
AU - MacLennan, Calman A
AU - Mutreja, Ankur
AU - Dougan, Gordon
PY - 2016/7/11
Y1 - 2016/7/11
N2 - There are still a significant number of bacterial infections for which no vaccines are available and several of the existing vaccines are suboptimal. However, the science of genomics is providing new approaches, including reverse vaccinology, identifying new candidate antigens, and assessing potential vaccine coverage. These advances are stimulating a reappraisal of the field and new candidate vaccines are emerging.
AB - There are still a significant number of bacterial infections for which no vaccines are available and several of the existing vaccines are suboptimal. However, the science of genomics is providing new approaches, including reverse vaccinology, identifying new candidate antigens, and assessing potential vaccine coverage. These advances are stimulating a reappraisal of the field and new candidate vaccines are emerging.
KW - Adjuvant
KW - Genomics
KW - Meningitis
KW - Oral
KW - Reverse vaccinology
UR - http://www.scopus.com/inward/record.url?scp=84987887275&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-802174-3.00016-3
DO - 10.1016/B978-0-12-802174-3.00016-3
M3 - Chapter (Book)
SN - 9780128021743
SP - 311
EP - 329
BT - The Vaccine Book: Second Edition
PB - Elsevier
ER -