Nevirapine

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Abstract

Nevirapine (previously known as BI-RG-587) is a dipyridodiazepinone derivative and a potent and highly specific inhibitor of the reverse transcriptase of HIV-1. It has no activity against HIV-2 or any other retrovirus. It is a member of a class of structurally diverse nonnucleoside reverse transcriptase inhibitor (NNRTI) compounds that share part, or all, of the same binding site on the HIV reverse transcriptase enzyme.

Original languageEnglish
Title of host publicationKucers the Use of Antibiotics
Subtitle of host publicationA Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs
EditorsM. Lindsay Grayson
Place of PublicationBoca Raton FL USA
PublisherCRC Press
Chapter235
Pages3855-3906
Number of pages52
Edition7th
ISBN (Electronic)9781498747967
ISBN (Print)9781498747950
Publication statusPublished - 2018

Cite this

Hoy, J. (2018). Nevirapine. In M. L. Grayson (Ed.), Kucers the Use of Antibiotics: A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs (7th ed., pp. 3855-3906). CRC Press.