Neurocognitive and self-efficacy benefits of cognitive remediation in schizophrenia: A randomized controlled trial

Shayden D. Bryce, Susan L. Rossell, Stuart J. Lee, Richard J. Lawrence, Eric J. Tan, Sean P. Carruthers, Jennie L. Ponsford

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21 Citations (Scopus)


Objectives: The aim of this study was to evaluate the impact of computer-assisted drill-and-strategy cognitive remediation (CR) for community-dwelling individuals with schizophrenia on cognition, everyday self-efficacy, and independent living skills. Methods: Fifty-six people with schizophrenia or schizoaffective disorder were randomized into CR or computer game (CG) playing (control), and offered twenty 1-hr individual sessions in a group setting over 10 weeks. Measures of cognition, psychopathology, self-efficacy, quality of life, and independent living skills were conducted at baseline, end-group and 3 months following intervention completion. Results: Forty-three participants completed at least 10 sessions and the end-group assessment. Linear mixed-effect analyses among completers demonstrated a significant interaction effect for global cognition favoring CR (p=.028). CR-related cognitive improvement was sustained at 3-months follow-up. At end-group, 17 (77%) CR completers showed a reliable improvement in at least one cognitive domain. A significant time effect was evident for self-efficacy (p=.028) with both groups improving over time, but no significant interaction effect was observed. No significant effects were found for other study outcomes, including the functional measure. Conclusions: Computer-assisted drill-and-strategy CR in schizophrenia improved cognitive test performance, while participation in both CR and CG playing promoted enhancements in everyday self-efficacy. Changes in independent living skills did not appear to result from CR, however. Adjunctive psychosocial rehabilitation is likely necessary for improvements in real-world community functioning to be achieved. (JINS, 2018, 24, 549-562)

Original languageEnglish
Pages (from-to)549-562
Number of pages14
JournalJournal of the International Neuropsychological Society
Issue number6
Publication statusPublished - 1 Jul 2018


  • cognition
  • enhancement
  • psychosis
  • rehabilitation.
  • self-confidence
  • training

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