Neuroanatomy of Feeding Pathways

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Abstract

An understanding of the neuroanatomy of feeding pathways has been a cornerstone of neuroscience and behavioral neuroscience research since the middle of the 1900s and remains fundamental not only to advances in the biology of ingestive behavior but to the elucidation of therapeutic directions to combat obesity. This chapter reviews the current trend to consider the interrelationships of distributed neural networks extending across brainstem, hypothalamic, midbrain, and cortical regions. While the list of key brain regions contributing to the distributed neural networks acting in concert to define appetite, feeding, and body weight is not meant to be exhaustive, it will serve as the basis for the description of central feeding pathways described. The chapter also explores the view of arcuate-centric circuitry, is that there will be a homeostatic balance in body weight; that is, a matching of appetite and expenditure on one hand with nutrient reserves on the other.

Original languageEnglish
Title of host publicationNeuroendocrinology of Appetite
EditorsSuzanne L. Dickson, Julian G. Mercer
Place of PublicationChichester UK
PublisherWiley-Blackwell
Pages1-23
Number of pages23
ISBN (Electronic)9781118839317
ISBN (Print)9781118839324
DOIs
Publication statusPublished - 22 Aug 2016

Keywords

  • Appetite control
  • Arcuate-centric circuit
  • Distributed neural networks
  • Hedonic feeding pathways
  • Hedonistic neural pathways
  • Homeostatic feeding pathways
  • Homeostatic neural pathways
  • Hypothalamic feeding-related pathways
  • Neuroendocrinology

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