Neonatal MRI is associated with future cognition and academic achievement in preterm children

Henrik Ullman, Megan Mary Spencer-Smith, Deanne K Thompson, Lex W Doyle, Terrie Eleanor Inder, Peter J. Anderson, Torkel Klingberg

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43 Citations (Scopus)

Abstract

School-age children born preterm are particularly at risk for low mathematical achievement, associated with reduced working memory and number skills. Early identification of preterm children at risk for future impairments using brain markers might assist in referral for early intervention. This study aimed to examine the use of neonatal magnetic resonance imaging measures derived from automated methods (Jacobian maps from deformation-based morphometry; fractional anisotropy maps from diffusion tensor images) to predict skills important for mathematical achievement (working memory, early mathematical skills) at 5 and 7 years in a cohort of preterm children using both univariable (general linear model) and multivariable models (support vector regression). Participants were preterm children born
Original languageEnglish
Pages (from-to)3251 - 3262
Number of pages12
JournalBrain
Volume138
Issue number11
DOIs
Publication statusPublished - 2015

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