Nanostructured Electrochemical Biosensors for Label-Free Detection of Water- and Food-Borne Pathogens

Nekane Reta, Christopher P. Saint, Andrew Michelmore, Beatriz Prieto-Simon, Nicolas H. Voelcker

Research output: Contribution to journalReview ArticleResearchpeer-review

47 Citations (Scopus)


The emergence of nanostructured materials has opened new horizons in the development of next generation biosensors. Being able to control the design of the electrode interface at the nanoscale combined with the intrinsic characteristics of the nanomaterials engenders novel biosensing platforms with improved capabilities. The purpose of this review is to provide a comprehensive and critical overview of the latest trends in emerging nanostructured electrochemical biosensors. A detailed description and discussion of recent approaches to construct label-free electrochemical nanostructured electrodes is given with special focus on pathogen detection for environmental monitoring and food safety. This includes the use of nanoscale materials such as nanotubes, nanowires, nanoparticles, and nanosheets as well as porous nanostructured materials including nanoporous anodic alumina, mesoporous silica, porous silicon, and polystyrene nanochannels. These platforms may pave the way toward the development of point-of-care portable electronic devices for applications ranging from environmental analysis to biomedical diagnostics.

Original languageEnglish
Pages (from-to)6055-6072
Number of pages18
JournalACS Applied Materials & Interfaces
Issue number7
Publication statusPublished - 21 Feb 2018


  • electrochemical biosensing
  • environmental monitoring
  • food safety
  • label-free detection
  • nanochannels
  • nanoscale materials
  • pathogen detection

Cite this