Nanoengineering of core-shell magnetic mesoporous microspheres with tunable surface roughness

Qin Yue, Yu Zhang, Yongjian Jiang, Jialuo Li, Hongwei Zhang, Chengzhong Yu, Ahmed A. Elzatahry, Abdulaziz Alghamdi, Yonghui Deng, Dongyuan Zhao

Research output: Contribution to journalArticleResearchpeer-review

89 Citations (Scopus)

Abstract

Functional core-shell mesoporous microspheres with integrated functions, controlled structure, and surface properties and morphologies have received increasing attention due to their excellent physicochemical properties. Herein, core-shell magnetic mesoporous materials with cauliflower-like morphology and tunable surface roughness have been synthesized through a kinetics-controlled interface co-assembly and deposition of mesostructured nanocomposites on Fe3O4@RF microspheres (RF refers to resorcinol formaldehyde resin). The obtained microspheres, synthesized via this interface nanoengineering method, possess well-defined sandwich structure with a tunable rough morphology, uniform size (560-1000 nm), perpendicularly aligned mesopores (∼5.7 nm) in the outer shell, RF-protected magnetic responsive core, high surface area up to 382 m2/g, and large pore volume of 0.66 cm3/g. As a result of the unique surface features and magnetic properties, these microspheres exhibit excellent performance in stabilizing and oxygen-free manipulating aqueous solutions in petroleum ether by a magnetic field. They also exhibit superior cell uptake properties compared with traditional smooth core-shell magnetic mesoporous silica microspheres, opening up the possible applications in fast drug delivery in cancer therapy.

Original languageEnglish
Pages (from-to)4954-4961
Number of pages8
JournalJournal of the American Chemical Society
Volume139
Issue number13
DOIs
Publication statusPublished - 5 Apr 2017
Externally publishedYes

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