NanoEHS beyond toxicity-focusing on biocorona

Sijie Lin, Monika Mortimer, Ran Chen, Aleksandr Kakinen, Jim E. Riviere, Thomas P Davis, Feng Ding, Pu-Chun Ke

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The first phase of studies on environmental health and safety of nanomaterials (nanoEHS) has been mainly focused on evidence-based investigations that probe the impact of nanoparticles, nanomaterials and nano-enabled products on biological and ecological systems. The integration of multiple disciplines, including colloidal science, nanomaterials science, chemistry, toxicology/immunology and environmental science, is necessary to understand the implications of nanotechnology for both human health and the environment. While strides have been made in connecting the physicochemical properties of nanomaterials with their hazard potential in tiered models, fundamental understanding of nano-biomolecular interactions and their implications for nanoEHS is largely absent from the literature. Research on nano-biomolecular interactions within the context of natural systems not only provides important clues for deciphering nanotoxicity and nanoparticle-induced pathology, but also presents vast new opportunities for screening beneficial material properties and designing greener products from the bottom up. This review highlights new opportunities concerning nano-biomolecular interactions beyond the scope of toxicity.

Original languageEnglish
Pages (from-to)1433-1454
Number of pages22
JournalEnvironmental Science: Nano
Volume4
Issue number7
DOIs
Publication statusPublished - 2017

Cite this

Lin, Sijie ; Mortimer, Monika ; Chen, Ran ; Kakinen, Aleksandr ; Riviere, Jim E. ; Davis, Thomas P ; Ding, Feng ; Ke, Pu-Chun. / NanoEHS beyond toxicity-focusing on biocorona. In: Environmental Science: Nano. 2017 ; Vol. 4, No. 7. pp. 1433-1454.
@article{29fa592d57d34e4bbabd77e4fe6fadee,
title = "NanoEHS beyond toxicity-focusing on biocorona",
abstract = "The first phase of studies on environmental health and safety of nanomaterials (nanoEHS) has been mainly focused on evidence-based investigations that probe the impact of nanoparticles, nanomaterials and nano-enabled products on biological and ecological systems. The integration of multiple disciplines, including colloidal science, nanomaterials science, chemistry, toxicology/immunology and environmental science, is necessary to understand the implications of nanotechnology for both human health and the environment. While strides have been made in connecting the physicochemical properties of nanomaterials with their hazard potential in tiered models, fundamental understanding of nano-biomolecular interactions and their implications for nanoEHS is largely absent from the literature. Research on nano-biomolecular interactions within the context of natural systems not only provides important clues for deciphering nanotoxicity and nanoparticle-induced pathology, but also presents vast new opportunities for screening beneficial material properties and designing greener products from the bottom up. This review highlights new opportunities concerning nano-biomolecular interactions beyond the scope of toxicity.",
author = "Sijie Lin and Monika Mortimer and Ran Chen and Aleksandr Kakinen and Riviere, {Jim E.} and Davis, {Thomas P} and Feng Ding and Pu-Chun Ke",
year = "2017",
doi = "10.1039/c6en00579a",
language = "English",
volume = "4",
pages = "1433--1454",
journal = "Environmental Science: Nano",
issn = "2051-8153",
publisher = "The Royal Society of Chemistry",
number = "7",

}

NanoEHS beyond toxicity-focusing on biocorona. / Lin, Sijie; Mortimer, Monika; Chen, Ran; Kakinen, Aleksandr; Riviere, Jim E.; Davis, Thomas P; Ding, Feng; Ke, Pu-Chun.

In: Environmental Science: Nano, Vol. 4, No. 7, 2017, p. 1433-1454.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - NanoEHS beyond toxicity-focusing on biocorona

AU - Lin, Sijie

AU - Mortimer, Monika

AU - Chen, Ran

AU - Kakinen, Aleksandr

AU - Riviere, Jim E.

AU - Davis, Thomas P

AU - Ding, Feng

AU - Ke, Pu-Chun

PY - 2017

Y1 - 2017

N2 - The first phase of studies on environmental health and safety of nanomaterials (nanoEHS) has been mainly focused on evidence-based investigations that probe the impact of nanoparticles, nanomaterials and nano-enabled products on biological and ecological systems. The integration of multiple disciplines, including colloidal science, nanomaterials science, chemistry, toxicology/immunology and environmental science, is necessary to understand the implications of nanotechnology for both human health and the environment. While strides have been made in connecting the physicochemical properties of nanomaterials with their hazard potential in tiered models, fundamental understanding of nano-biomolecular interactions and their implications for nanoEHS is largely absent from the literature. Research on nano-biomolecular interactions within the context of natural systems not only provides important clues for deciphering nanotoxicity and nanoparticle-induced pathology, but also presents vast new opportunities for screening beneficial material properties and designing greener products from the bottom up. This review highlights new opportunities concerning nano-biomolecular interactions beyond the scope of toxicity.

AB - The first phase of studies on environmental health and safety of nanomaterials (nanoEHS) has been mainly focused on evidence-based investigations that probe the impact of nanoparticles, nanomaterials and nano-enabled products on biological and ecological systems. The integration of multiple disciplines, including colloidal science, nanomaterials science, chemistry, toxicology/immunology and environmental science, is necessary to understand the implications of nanotechnology for both human health and the environment. While strides have been made in connecting the physicochemical properties of nanomaterials with their hazard potential in tiered models, fundamental understanding of nano-biomolecular interactions and their implications for nanoEHS is largely absent from the literature. Research on nano-biomolecular interactions within the context of natural systems not only provides important clues for deciphering nanotoxicity and nanoparticle-induced pathology, but also presents vast new opportunities for screening beneficial material properties and designing greener products from the bottom up. This review highlights new opportunities concerning nano-biomolecular interactions beyond the scope of toxicity.

UR - http://www.scopus.com/inward/record.url?scp=85024105802&partnerID=8YFLogxK

U2 - 10.1039/c6en00579a

DO - 10.1039/c6en00579a

M3 - Article

VL - 4

SP - 1433

EP - 1454

JO - Environmental Science: Nano

JF - Environmental Science: Nano

SN - 2051-8153

IS - 7

ER -