Nano-drug delivery system: a promising approach against breast cancer

Jonaid Ahmad Malik, Jeba Ajgar Ansari, Sakeel Ahmed, Afreen Khan, Nafees Ahemad, Sirajudheen Anwar

Research output: Contribution to journalReview ArticleOtherpeer-review

3 Citations (Scopus)

Abstract

Breast cancer(BC) is among the most frequent malignancies women face around the globe. Nanotherapeutics are constantly evolving to overcome the limitations of conventional diagnostic and therapeutic approaches. Nanotechnology-based nanocarriers have a higher entrapment efficiency, low cytotoxicity, greater stability and improved half-life than conventional therapy. Nano-drug delivery systems have improved pharmacokinetics and pharmacodynamics parameters because of nanomeric size. Currently, various nano-formulations are in preclinical and clinical settings for breast cancer, like polymeric nanoparticles, micelles, nanobodies, magnetic nanoparticles, liposomes, niosomes, gold-nanoparticles, dendrimers and carbon-nanotubes. This review highlights the recent advancement in developing nano-drug delivery systems for BC treatment. This review will open the gateway to researchers to understand the current approaches to developing nano-formulation and improving problems associated with conventional therapy.

Original languageEnglish
Pages (from-to)357-381
Number of pages25
JournalTherapeutic Delivery
Volume14
Issue number5
DOIs
Publication statusPublished - 1 May 2023

Keywords

  • breast cancer
  • breast cancer treatment
  • cytotoxicity
  • nano-drug delivery systems
  • nanotechnology

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