Nano-architecture

Creating complex surface structures using supramolecular self-assembly of tripeptides

Adam Mechler, Rania S Seoudi, Mark P. Del Borgo, Marie Isabel Aguilar, Patrick Perlmutter

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

Abstract

Here we report on using small unnatural helical beta peptides to form higher order geometries. These peptides are known to self-assemble by supramolecular recognition, via a unique 3-point H-bonding motif. This self-assembly pattern leads to unprecedented head-to-tail self-assembly, thus continuing the intramolecular helix into a fibrous superstructure. The smallest peptide still capable of self-assembly had a sequence of only three beta amino acids. We demonstrated a hierarchical self-assembly process, which can be designed to form macroscopic silk-like threads as well as complex nanometer scale surface structures. We have achieved radial as well as parallel geometries. Both the synthesis and the derivatization of the fibres is relatively straigthforward, making this platform technology ideally suited for the highly exacting requirements of materials science.

Original languageEnglish
Title of host publicationMicro/Nano Materials, Devices, and Systems
Volume8923
DOIs
Publication statusPublished - 2013
EventConference on Micro/Nano Materials, Devices, and Systems 2013 - RMIT University, Melbourne, Australia
Duration: 9 Dec 201311 Dec 2013

Conference

ConferenceConference on Micro/Nano Materials, Devices, and Systems 2013
CountryAustralia
CityMelbourne
Period9/12/1311/12/13
OtherProceedings of SPIE Vol. 8923

Keywords

  • artificial silk
  • self-assembly
  • supramolecular recognition
  • unnatural β-peptide

Cite this

Mechler, A., Seoudi, R. S., Del Borgo, M. P., Aguilar, M. I., & Perlmutter, P. (2013). Nano-architecture: Creating complex surface structures using supramolecular self-assembly of tripeptides. In Micro/Nano Materials, Devices, and Systems (Vol. 8923). [892301] https://doi.org/10.1117/12.2053914
Mechler, Adam ; Seoudi, Rania S ; Del Borgo, Mark P. ; Aguilar, Marie Isabel ; Perlmutter, Patrick. / Nano-architecture : Creating complex surface structures using supramolecular self-assembly of tripeptides. Micro/Nano Materials, Devices, and Systems. Vol. 8923 2013.
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Mechler, A, Seoudi, RS, Del Borgo, MP, Aguilar, MI & Perlmutter, P 2013, Nano-architecture: Creating complex surface structures using supramolecular self-assembly of tripeptides. in Micro/Nano Materials, Devices, and Systems. vol. 8923, 892301, Conference on Micro/Nano Materials, Devices, and Systems 2013, Melbourne, Australia, 9/12/13. https://doi.org/10.1117/12.2053914

Nano-architecture : Creating complex surface structures using supramolecular self-assembly of tripeptides. / Mechler, Adam; Seoudi, Rania S; Del Borgo, Mark P.; Aguilar, Marie Isabel; Perlmutter, Patrick.

Micro/Nano Materials, Devices, and Systems. Vol. 8923 2013. 892301.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

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