N-acetyl endorphin in rat spermatogonia and primary spermatocytes

M. C. Cheng, J. A. Clements, A. I. Smith, S. J. Lolait, J. W. Funder

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In previous reports modest levels of β-endorphin have been found by radioimmunoassay in rat testis, and localized by immunofluorescence to the interstitial cells. We have confirmed these previous reports and extended them by showing that the majority of testicular endorphins are acetylated forms, N-acetyl γ-endorphin, N-acetyl α-endorphin, and N-acetyl β-endorphin1-27. In addition, N-acetylated endorphins are not found in interstitial cells, but are confined to spermatogonia and primary spermatocytes.

Original languageEnglish
Pages (from-to)832-835
Number of pages4
JournalThe Journal of Clinical Investigation
Issue number3
Publication statusPublished - 1 Jan 1985

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