Mycobacterium abscessus Complex - A Particular Challenge in the Setting of Lung Transplantation

O. Smibert, G. I. Snell, H. Bills, G. P. Westall, C. O. Morrissey

Research output: Contribution to journalReview ArticleResearchpeer-review

14 Citations (Scopus)

Abstract

Mycobacterium abscessus complex is an emerging pathogen in lung transplant candidates and recipients. M. abscessus complex is widespread in the environment and can cause pulmonary, skin and soft tissue, and disseminated infection, particularly in lung transplant recipients. It is innately resistant to many antibiotics making it difficult to treat. Herein we describe the epidemiology, clinical manifestations, diagnosis and treatment of M. abscessus with an emphasis on lung transplant candidates and recipients. We also outline the areas where data are lacking and the areas where further research is urgently needed.

Original languageEnglish
Pages (from-to)325-333
Number of pages9
JournalExpert Review of Anti-Infective Therapy
Volume14
Issue number3
DOIs
Publication statusPublished - 3 Mar 2016

Keywords

  • diagnosis
  • infection
  • lung transplantation
  • Macrolides
  • Mycobacterium abscessus complex
  • Non tuberculous mycobacterium
  • treatment

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