Muscarinic M1 receptor sequence: preliminary studies on its effects on cognition and expression

Elizabeth Scarr, Suresh Sundram, Azita Khademy-Deljo, Tiffany F Cowie, Andrew Stuart Gibbons, Susan Juzva, Andrew James Mackinnon, Stephen J Wood, Renee Rebecca Testa, Christos Pantelis, Brian Dean

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Abstract

It has been reported that people with schizophrenia who are homozygous at the c.267C>A single nucleotide polymorphism of the cholinergic muscarinic M1 receptor (CHRM1) perform less well on the Wisconsin Card Sorting Test than those who are heterozygous. We investigated whether CHRM1 sequence is associated with impaired executive function, a common problem in schizophrenia
Original languageEnglish
Pages (from-to)94 - 98
Number of pages5
JournalSchizophrenia Research
Volume138
Issue number1
DOIs
Publication statusPublished - 2012

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