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Murine models of bone sarcomas

Camille Jacques, Nathalie Renema, Benjamin Ory, Carl R. Walkley, Agamemnon E. Grigoriadis, Dominique Heymann

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Abstract

This chapter describes the procedures for inducing bone sarcoma in mice. Two models based on inoculation of cancer cells in paraosseous and intraosseous site will be described. In addition to providing technical aspects of anesthesia and surgical options, key information of cell preparation and postoperative follow-up will be discussed.

Original languageEnglish
Title of host publicationBone Research Protocols
EditorsAymen I. Idris
Place of PublicationNew York NY USA
PublisherHumana Press
Chapter18
Pages331-342
Number of pages12
Edition3rd
ISBN (Electronic)9781493989973
ISBN (Print)9781493989966
DOIs
Publication statusPublished - 2019
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1914
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Bone sarcoma
  • Cell-injection
  • Chondrosarcoma
  • Ewing sarcoma
  • Genetically-engineered mouse models
  • Murine preclinical models
  • Osteosarcoma

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