TY - JOUR
T1 - Mumps vaccine associated orchitis: Evidence supporting a potential immune-mediated mechanism
AU - Clifford, Vanessa
AU - Wadsley, Jane
AU - Jenner, Bernard
AU - Buttery, James
PY - 2010
Y1 - 2010
N2 - We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literature regarding post-vaccine orchitis, highlight uncertainty regarding the pathogenesis of post-vaccine orchitis.
AB - We report 3 cases of orchitis following vaccination with mumps-measles-rubella (MMR) vaccine, two with an onset within 3 days following vaccination. Orchitis is a common complication of mumps infection, particularly in post-pubertal males, and is also recognized as a very rare complication of mumps vaccination. These cases, discussed together with a comprehensive review of the existing literature regarding post-vaccine orchitis, highlight uncertainty regarding the pathogenesis of post-vaccine orchitis.
UR - http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6TD4-4Y5X5R1-5-1&_cdi=5188&_user=542840&_pii=S0264410X1000037X&_origin=gateway&_coverDate=03%
U2 - 10.1016/j.vaccine.2010.01.007
DO - 10.1016/j.vaccine.2010.01.007
M3 - Article
SN - 0264-410X
VL - 28
SP - 2671
EP - 2673
JO - Vaccine
JF - Vaccine
IS - 14
ER -
