Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials

Yingyue Zhu; Wei Chen; Ruirui Qiao; Zhengyu Jin; Chuanlai  Xu

doi:10.1109/INEC.2010.5424838

Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials

Yingyue Zhu, Wei Chen, Ruirui Qiao, Zhengyu Jin, Chuanlai Xu

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other › peer-review

Abstract

A novel transfection vector was designed to deliver the antisense oligodeoxynucleotide into the cancer cells (HL-60). Antisense oligodeoxynucleotides (ASODNs) were conjugated to the gold nanoparticles (GNPs) through a chemical reaction. The conjugates were then bound to the single-walled carbon nanotubes (SWNTs). This vector system can effectively for induced apoptosis of the cancer cells. The gold nanoparticles helped to improve both transfection and Raman signal. This vector system can effectively for induced apoptosis of the cancer cells, and thus has the potential to be used as a cancer therapy.

Original language	English
Title of host publication	INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings
Pages	1385-1386
Number of pages	2
DOIs	https://doi.org/10.1109/INEC.2010.5424838
Publication status	Published - 2010
Externally published	Yes
Event	IEEE International Nanoelectronics Conference 2010 - Hongkong, China Duration: 3 Jan 2010 → 8 Jan 2010 Conference number: 3rd https://ieeexplore.ieee.org/xpl/conhome/5416830/proceeding (Proceedings)

Conference

Conference	IEEE International Nanoelectronics Conference 2010
Abbreviated title	INEC 2010
Country/Territory	China
City	Hongkong
Period	3/01/10 → 8/01/10
Internet address	https://ieeexplore.ieee.org/xpl/conhome/5416830/proceeding (Proceedings)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/INEC.2010.5424838

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Zhu, Y., Chen, W., Qiao, R., Jin, Z., & Xu, C. (2010). Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials. In INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings (pp. 1385-1386). Article 5424838 https://doi.org/10.1109/INEC.2010.5424838

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title = "Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials",

abstract = "A novel transfection vector was designed to deliver the antisense oligodeoxynucleotide into the cancer cells (HL-60). Antisense oligodeoxynucleotides (ASODNs) were conjugated to the gold nanoparticles (GNPs) through a chemical reaction. The conjugates were then bound to the single-walled carbon nanotubes (SWNTs). This vector system can effectively for induced apoptosis of the cancer cells. The gold nanoparticles helped to improve both transfection and Raman signal. This vector system can effectively for induced apoptosis of the cancer cells, and thus has the potential to be used as a cancer therapy.",

author = "Yingyue Zhu and Wei Chen and Ruirui Qiao and Zhengyu Jin and Chuanlai Xu",

year = "2010",

doi = "10.1109/INEC.2010.5424838",

language = "English",

isbn = "9781424435449",

pages = "1385--1386",

booktitle = "INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings",

note = "IEEE International Nanoelectronics Conference 2010, INEC 2010 ; Conference date: 03-01-2010 Through 08-01-2010",

url = "https://ieeexplore.ieee.org/xpl/conhome/5416830/proceeding",

}

Zhu, Y, Chen, W, Qiao, R, Jin, Z & Xu, C 2010, Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials. in INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings., 5424838, pp. 1385-1386, IEEE International Nanoelectronics Conference 2010, Hongkong, China, 3/01/10. https://doi.org/10.1109/INEC.2010.5424838

Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials. / Zhu, Yingyue; Chen, Wei; Qiao, Ruirui et al.
INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings. 2010. p. 1385-1386 5424838.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other › peer-review

TY - GEN

T1 - Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials

AU - Zhu, Yingyue

AU - Chen, Wei

AU - Qiao, Ruirui

AU - Jin, Zhengyu

AU - Xu, Chuanlai

N1 - Conference code: 3rd

PY - 2010

Y1 - 2010

N2 - A novel transfection vector was designed to deliver the antisense oligodeoxynucleotide into the cancer cells (HL-60). Antisense oligodeoxynucleotides (ASODNs) were conjugated to the gold nanoparticles (GNPs) through a chemical reaction. The conjugates were then bound to the single-walled carbon nanotubes (SWNTs). This vector system can effectively for induced apoptosis of the cancer cells. The gold nanoparticles helped to improve both transfection and Raman signal. This vector system can effectively for induced apoptosis of the cancer cells, and thus has the potential to be used as a cancer therapy.

AB - A novel transfection vector was designed to deliver the antisense oligodeoxynucleotide into the cancer cells (HL-60). Antisense oligodeoxynucleotides (ASODNs) were conjugated to the gold nanoparticles (GNPs) through a chemical reaction. The conjugates were then bound to the single-walled carbon nanotubes (SWNTs). This vector system can effectively for induced apoptosis of the cancer cells. The gold nanoparticles helped to improve both transfection and Raman signal. This vector system can effectively for induced apoptosis of the cancer cells, and thus has the potential to be used as a cancer therapy.

UR - http://www.scopus.com/inward/record.url?scp=77951661163&partnerID=8YFLogxK

U2 - 10.1109/INEC.2010.5424838

DO - 10.1109/INEC.2010.5424838

M3 - Conference Paper

AN - SCOPUS:77951661163

SN - 9781424435449

SP - 1385

EP - 1386

BT - INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings

T2 - IEEE International Nanoelectronics Conference 2010

Y2 - 3 January 2010 through 8 January 2010

ER -

Multifunctional vectors system for cancer therapy using single-walled carbon nanotubes and antisense oligonucleotide-modified gold nanoparticles composite materials

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UN SDGs

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