Abstract
Dysregulated interactions between the host immune system and gut microbiota can underpin inflammation, leading to colorectal cancer (CRC). In this issue of Cancer Cell, Kesselring et al. reveal a bimodal role of the TLR/IL-1R-signaling negative regulator, IRAK-M, in promoting tumoral microbial colonization and STAT3 oncoprotein stabilization during CRC.
Original language | English |
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Pages (from-to) | 615-617 |
Number of pages | 3 |
Journal | Cancer Cell |
Volume | 29 |
Issue number | 5 |
DOIs | |
Publication status | Published - 9 May 2016 |