Multifaceted Role of IRAK-M in the Promotion of Colon Carcinogenesis via Barrier Dysfunction and STAT3 Oncoprotein Stabilization in Tumors

Brendan J. Jenkins

Research output: Contribution to journal › Short Survey › Other › peer-review

2 Citations (Scopus)

Abstract

Dysregulated interactions between the host immune system and gut microbiota can underpin inflammation, leading to colorectal cancer (CRC). In this issue of Cancer Cell, Kesselring et al. reveal a bimodal role of the TLR/IL-1R-signaling negative regulator, IRAK-M, in promoting tumoral microbial colonization and STAT3 oncoprotein stabilization during CRC.

Original languageEnglish
Pages (from-to)615-617
Number of pages3
JournalCancer Cell
Volume29
Issue number5
DOIs
Publication statusPublished - 9 May 2016

Cite this

Jenkins, Brendan J. / Multifaceted Role of IRAK-M in the Promotion of Colon Carcinogenesis via Barrier Dysfunction and STAT3 Oncoprotein Stabilization in Tumors. In: Cancer Cell. 2016 ; Vol. 29, No. 5. pp. 615-617.
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abstract = "Dysregulated interactions between the host immune system and gut microbiota can underpin inflammation, leading to colorectal cancer (CRC). In this issue of Cancer Cell, Kesselring et al. reveal a bimodal role of the TLR/IL-1R-signaling negative regulator, IRAK-M, in promoting tumoral microbial colonization and STAT3 oncoprotein stabilization during CRC.",
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Jenkins, BJ 2016, 'Multifaceted Role of IRAK-M in the Promotion of Colon Carcinogenesis via Barrier Dysfunction and STAT3 Oncoprotein Stabilization in Tumors', Cancer Cell, vol. 29, no. 5, pp. 615-617. https://doi.org/10.1016/j.ccell.2016.04.008

Multifaceted Role of IRAK-M in the Promotion of Colon Carcinogenesis via Barrier Dysfunction and STAT3 Oncoprotein Stabilization in Tumors. / Jenkins, Brendan J.

In: Cancer Cell, Vol. 29, No. 5, 09.05.2016, p. 615-617.

Research output: Contribution to journal › Short Survey › Other › peer-review

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AB - Dysregulated interactions between the host immune system and gut microbiota can underpin inflammation, leading to colorectal cancer (CRC). In this issue of Cancer Cell, Kesselring et al. reveal a bimodal role of the TLR/IL-1R-signaling negative regulator, IRAK-M, in promoting tumoral microbial colonization and STAT3 oncoprotein stabilization during CRC.

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JO - Cancer Cell

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Jenkins BJ. Multifaceted Role of IRAK-M in the Promotion of Colon Carcinogenesis via Barrier Dysfunction and STAT3 Oncoprotein Stabilization in Tumors. Cancer Cell. 2016 May 9;29(5):615-617. https://doi.org/10.1016/j.ccell.2016.04.008

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