mtDNA caught in the act again

Kate McArthur; Benjamin T. Kile

doi:10.1038/s41556-024-01345-7

mtDNA caught in the act again

Kate McArthur, Benjamin T. Kile

Research output: Contribution to journal › Comment / Debate › Other › peer-review

1 Citation (Scopus)

Abstract

Despite a growing understanding of the immunostimulatory properties of mitochondrial DNA (mtDNA), little is known about how and why mtDNA escapes its mitochondrial confines. A study now describes an endosomal trafficking pathway that facilitates mtDNA egress and provides an additional mechanism of mtDNA release in vitro.

Original language	English
Pages (from-to)	177-178
Number of pages	2
Journal	Nature Cell Biology
Volume	26
Issue number	2
DOIs	https://doi.org/10.1038/s41556-024-01345-7
Publication status	Published - Feb 2024

Access to Document

10.1038/s41556-024-01345-7

Cite this

@article{093dd9be898043349dd3e9859c871338,

title = "mtDNA caught in the act again",

abstract = "Despite a growing understanding of the immunostimulatory properties of mitochondrial DNA (mtDNA), little is known about how and why mtDNA escapes its mitochondrial confines. A study now describes an endosomal trafficking pathway that facilitates mtDNA egress and provides an additional mechanism of mtDNA release in vitro.",

author = "Kate McArthur and Kile, \{Benjamin T.\}",

note = "Publisher Copyright: {\textcopyright} Springer Nature Limited 2024.",

year = "2024",

month = feb,

doi = "10.1038/s41556-024-01345-7",

language = "English",

volume = "26",

pages = "177--178",

journal = "Nature Cell Biology",

issn = "1465-7392",

publisher = "Nature Publishing Group",

number = "2",

}

TY - JOUR

T1 - mtDNA caught in the act again

AU - McArthur, Kate

AU - Kile, Benjamin T.

N1 - Publisher Copyright: © Springer Nature Limited 2024.

PY - 2024/2

Y1 - 2024/2

N2 - Despite a growing understanding of the immunostimulatory properties of mitochondrial DNA (mtDNA), little is known about how and why mtDNA escapes its mitochondrial confines. A study now describes an endosomal trafficking pathway that facilitates mtDNA egress and provides an additional mechanism of mtDNA release in vitro.

AB - Despite a growing understanding of the immunostimulatory properties of mitochondrial DNA (mtDNA), little is known about how and why mtDNA escapes its mitochondrial confines. A study now describes an endosomal trafficking pathway that facilitates mtDNA egress and provides an additional mechanism of mtDNA release in vitro.

UR - https://www.scopus.com/pages/publications/85184415205

U2 - 10.1038/s41556-024-01345-7

DO - 10.1038/s41556-024-01345-7

M3 - Comment / Debate

C2 - 38332352

AN - SCOPUS:85184415205

SN - 1465-7392

VL - 26

SP - 177

EP - 178

JO - Nature Cell Biology

JF - Nature Cell Biology

IS - 2

ER -

mtDNA caught in the act again

Abstract

Access to Document

Other files and links

Cite this