MR-based attenuation map re-alignment and motion correction in simultaneous brain MR-PET imaging

Francesco Sforazzini, Zhaolin Chen, Jakub Baran, Jason Bradley, Alexandra Carey, N. Jon Shah, Gary Egan

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

2 Citations (Scopus)


Head movement is a major issue in dynamic PET imaging. A simultaneous MR-PET scanner is capable of acquiring both MR and PET data concurrently, which enables opportunities to use MR information for PET motion correction. Here we propose an MR-based method to detect head motion and to correct motion artefacts during PET image reconstruction. The method is based on co-registration of multiple MR contrasts to extract motion parameters. The motion parameters are then used to guide the Multiple Acquisition Frame (MAF) algorithm to bin the PET list-mode data into multiple frames whenever significant motion occurs. Furthermore, motion parameters are used to re-align the PET attenuation u-map to each frame prior to the image reconstruction. Finally, PET images are reconstructed for each frame and combined to produce a final image. Using both phantom and in-vivo human data, we show that this method can significantly increase image quality and reduce motion artefacts.

Original languageEnglish
Title of host publication2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017)
EditorsSimon Warfield, Arrate Munoz Barrutia
Place of PublicationPiscataway NJ USA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Number of pages4
ISBN (Electronic)9781509011728
ISBN (Print)9781509011735
Publication statusPublished - 15 Jun 2017
EventIEEE International Symposium on Biomedical Imaging (ISBI) 2017 - Melbourne Convention and Exhibition Centre, Melbourne, Australia
Duration: 18 Apr 201721 Apr 2017
Conference number: 14th


ConferenceIEEE International Symposium on Biomedical Imaging (ISBI) 2017
Abbreviated titleISBI 2017
OtherISBI is a joint initiative from the IEEE Signal Processing Society (SPS) and the IEEE Engineering in Medicine and Biology Society (EMBS). The 2017 meeting will include tutorials, and a scientific program composed of plenary talks, invited special sessions, challenges, as well as oral and poster presentations of peer-reviewed papers.
Internet address


  • Attenuation correction
  • Motion correction
  • Simultaneous MR-PET

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