Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: The Dialysis Outcomes and Practice Patterns Study (DOPPS)

Francesca Tentori, Margaret J Blayney, Justin M Albert, Brenda Gillespie, Peter Kerr, Jurgen Bommer, Eric W Young, Tadao Akizawa, Takashi Akiba, Ronald L Pisoni, Bruce M Robinson, Friedrich K Port

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Abstract

BACKGROUND: Abnormalities in serum calcium, phosphorus, and parathyroid hormone (PTH) concentrations are common in patients with chronic kidney disease and have been associated with increased morbidity and mortality. No clinical trials have been conducted to clearly identify categories of calcium, phosphorus, and PTH levels associated with the lowest mortality risk. Current clinical practice guidelines are based largely on expert opinions, and clinically relevant differences exist among guidelines across countries. We sought to describe international trends in calcium, phosphorus, and PTH levels during 10 years and identify mortality risk categories in the Dialysis Outcomes and Practice Patterns Study (DOPPS), an international study of hemodialysis practices and associated outcomes. STUDY DESIGN: Prospective cohort study.
Original languageEnglish
Pages (from-to)519 - 530
Number of pages12
JournalAmerican Journal of Kidney Diseases
Volume52
Issue number3
Publication statusPublished - 2008

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