Monofunctional electrophilic and nucleophilic derivatives of meso-tetraphenylporphyrin for attachment to peptides

Susan E. Matthews, Colin W. Pouton, Michael D. Threadgill

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Abstract

4-Nitrophenyl N-[4-(10,15,20-triphenylporphyrin-5-yl)phenyl]carbamate and 5-[4-(N-glycylamino)phenyl]-10,15,20-triphenylporphyrin have been synthesised from a readily prepared monofunctionalised porphyrin; they couple efficiently with the side-chains of extended lysyl and glutamyl peptide derivatives, respectively.

Original languageEnglish
Pages (from-to)1809-1811
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number17
DOIs
Publication statusPublished - 1 Dec 1995
Externally publishedYes

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