Abstract
Details of laboratory and preclinical tests that we have used to verify the electrical functionality of the device are described. A description of the surgical method that has been developed for implanting tiles in the visual cortex is provided, which will be used to demonstrate proof-of-concept of the system in first-in-human studies. Highlighted is the importance of post-surgical device calibration, psychophysics testing and training of recipients in using the system in both controlled and unsupervised environments. Signal processing algorithms that have been developedto enhance the user experience are described and details provided of how these have been tested to optimise their integration into the full system. Finally, we describe how the Gennaris technology can be applied to a broad spectrum of other technological and health-related challenges.
| Original language | English |
|---|---|
| Title of host publication | Artificial Vision |
| Subtitle of host publication | A Clinical Guide |
| Editors | Viet Peter Gabel |
| Place of Publication | Cham, Switzerland |
| Publisher | Springer |
| Pages | 215-225 |
| Number of pages | 11 |
| ISBN (Electronic) | 9783319418766 |
| ISBN (Print) | 9783319418742 |
| DOIs | |
| Publication status | Published - 2017 |
Keywords
- Cortical stimulation
- Bionic vision
- Wireless link
- Implant tile
- Hermetic
- Penetrating electrodes
- Annulus
- Neurosurgery
- Neural plasticity
- Academic-industry partnership
Cite this
}
Monash Vision Group's Gennaris cortical implant for vision restoration. / Lowery, Arthur James; Rosenfeld, Jeffrey V.; Rosa, Marcello G. P.; Brunton, Emma; Rajan, Ramesh; Mann, Collette; Armstrong, Mark; Mohan, Anand; Josh, Horace; Kleeman, Lindsay; Li, Wai Ho; Pritchard, Jeanette.
Artificial Vision: A Clinical Guide. ed. / Viet Peter Gabel. Cham, Switzerland : Springer, 2017. p. 215-225.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review
TY - CHAP
T1 - Monash Vision Group's Gennaris cortical implant for vision restoration
AU - Lowery, Arthur James
AU - Rosenfeld, Jeffrey V.
AU - Rosa, Marcello G. P.
AU - Brunton, Emma
AU - Rajan, Ramesh
AU - Mann, Collette
AU - Armstrong, Mark
AU - Mohan, Anand
AU - Josh, Horace
AU - Kleeman, Lindsay
AU - Li, Wai Ho
AU - Pritchard, Jeanette
PY - 2017
Y1 - 2017
N2 - The Gennaris bionic vision system is a wireless device that has been designed to directly stimulate the primary visual cortex to restore useful vision to people with bilateral, irreversible blindness. Here, we describe the end-to-end system and the design of each component. The rationale for design decisions is provided,including the benefits of cortical stimulation, the need for wireless power and data transmission and the format of the autonomous implant tiles and penetrating micro-electrode arrays. We discuss the broad population of people for which this device may provide benefit, with reference to specific indications of blindness. Details of laboratory and preclinical tests that we have used to verify the electrical functionality of the device are described. A description of the surgical method that has been developed for implanting tiles in the visual cortex is provided, which will be used to demonstrate proof-of-concept of the system in first-in-human studies. Highlighted is the importance of post-surgical device calibration, psychophysics testing and training of recipients in using the system in both controlled and unsupervised environments. Signal processing algorithms that have been developedto enhance the user experience are described and details provided of how these have been tested to optimise their integration into the full system. Finally, we describe how the Gennaris technology can be applied to a broad spectrum of other technological and health-related challenges.
AB - The Gennaris bionic vision system is a wireless device that has been designed to directly stimulate the primary visual cortex to restore useful vision to people with bilateral, irreversible blindness. Here, we describe the end-to-end system and the design of each component. The rationale for design decisions is provided,including the benefits of cortical stimulation, the need for wireless power and data transmission and the format of the autonomous implant tiles and penetrating micro-electrode arrays. We discuss the broad population of people for which this device may provide benefit, with reference to specific indications of blindness. Details of laboratory and preclinical tests that we have used to verify the electrical functionality of the device are described. A description of the surgical method that has been developed for implanting tiles in the visual cortex is provided, which will be used to demonstrate proof-of-concept of the system in first-in-human studies. Highlighted is the importance of post-surgical device calibration, psychophysics testing and training of recipients in using the system in both controlled and unsupervised environments. Signal processing algorithms that have been developedto enhance the user experience are described and details provided of how these have been tested to optimise their integration into the full system. Finally, we describe how the Gennaris technology can be applied to a broad spectrum of other technological and health-related challenges.
KW - Cortical stimulation
KW - Bionic vision
KW - Wireless link
KW - Implant tile
KW - Hermetic
KW - Penetrating electrodes
KW - Annulus
KW - Neurosurgery
KW - Neural plasticity
KW - Academic-industry partnership
UR - http://www.springer.com/la/book/9783319418742
U2 - 10.1007/978-3-319-41876-6
DO - 10.1007/978-3-319-41876-6
M3 - Chapter (Book)
SN - 9783319418742
SP - 215
EP - 225
BT - Artificial Vision
A2 - Gabel, Viet Peter
PB - Springer
CY - Cham, Switzerland
ER -