TY - JOUR
T1 - Molecules of interest – embelin – a review
AU - Othman, Siti Nurul Najiha
AU - Lum, Pei Teng
AU - Sekar, Mahendran
AU - Mazlan, Nurul Azima
AU - Yusri, Puteri Zarith Sofea
AU - Ghazali, Nurin Fatini
AU - Idi, Hikmah Mohd
AU - Azman, Shazalyana
AU - Ismail, Masitah
AU - Noor, Aina Akmal Mohd
N1 - Funding Information:
The authors would like to thank Ministry of Higher Education (MOHE) Malaysia for the financial support through Fundamental Research Grant Scheme [FRGS/1/2018/SKK10/UNIKL/02/1].
Publisher Copyright:
© RJPT All right reserved.
PY - 2020/7
Y1 - 2020/7
N2 - Embelin (2,5-dihydroxy-3-undecyl-1,4-benzoquinone) is an alkyl substituted hydroxy quinone isolated from numerous medicinal plants and mainly from Embelia ribes. It exhibits a wide range of biological activities and also in numerous cases is accountable for the traditional practice of its natural sources. It has been shown to reveal various pharmacological activities, and thus has several possible applications in clinical research. This review presents a comprehensive literature search of diverse studies carried out on embelin, especially its antidiabetic, cardioprotective, neuroprotective, anti-inflammatory, antiviral, antimicrobial, antioxidant, wound healing antifertility, analgesic and anticancer activities. The importance of the present review is on the chemistry and biological activities of embelin in addition to coherent and environmentally acceptable methods for establishment of this natural compound on a huge scale. Therefore, further research may help in exploiting its properties and emergent phyto-pharmaceuticals based on it.
AB - Embelin (2,5-dihydroxy-3-undecyl-1,4-benzoquinone) is an alkyl substituted hydroxy quinone isolated from numerous medicinal plants and mainly from Embelia ribes. It exhibits a wide range of biological activities and also in numerous cases is accountable for the traditional practice of its natural sources. It has been shown to reveal various pharmacological activities, and thus has several possible applications in clinical research. This review presents a comprehensive literature search of diverse studies carried out on embelin, especially its antidiabetic, cardioprotective, neuroprotective, anti-inflammatory, antiviral, antimicrobial, antioxidant, wound healing antifertility, analgesic and anticancer activities. The importance of the present review is on the chemistry and biological activities of embelin in addition to coherent and environmentally acceptable methods for establishment of this natural compound on a huge scale. Therefore, further research may help in exploiting its properties and emergent phyto-pharmaceuticals based on it.
KW - Anti-inflammatory
KW - Anticancer
KW - Antidiabetic
KW - Antifertility
KW - Benzoquinone
KW - Cardioprotective
KW - Embelin
KW - Neuroprotective
UR - https://www.scopus.com/pages/publications/85091630983
U2 - 10.5958/0974-360X.2020.00618.6
DO - 10.5958/0974-360X.2020.00618.6
M3 - Review Article
AN - SCOPUS:85091630983
SN - 0974-3618
VL - 13
SP - 3485
EP - 3493
JO - Research Journal of Pharmacy and Technology
JF - Research Journal of Pharmacy and Technology
IS - 7
ER -