Molecular Genetics of Inflammatory Bowel Disease

Charlotte Hedin, John D. Rioux, Mauro D'Amato

Research output: Book/ReportEdited BookOtherpeer-review

Abstract

Inflammatory bowel disease (IBD) affects 1% of people worldwide. This condition is partly inherited, and genetic research has made enormous progress during the last few years, providing important insight into disease pathogenesis. This book provides a concise but complete overview of existing knowledge, with particular focus on the molecular and genetic mechanisms at the basis of IBD.

Invited experts, at the frontline of IBD research, introduce basic concepts in the pathophysiology of IBD and its two major forms Crohn’s disease and ulcerative colitis, provide a historical perspective and highlight latest discoveries of IBD genetic research, describe how this information has helped to unravel novel pathogenetic pathways, and formulate a vision for future investigations and their clinical application in IBD.

State-of-the-art information contained in this book is an exceptional resource for all those in the biomedical field with a specific interest in IBD, including basic scientists, gastroenterologists, GI specialist doctors and research nurses, but also medical and biomedical students.
Original languageEnglish
Place of PublicationSwitzerland
PublisherSpringer
Number of pages399
Edition2nd
ISBN (Electronic)9783030287030
ISBN (Print)9783030287023
DOIs
Publication statusPublished - 2019

Keywords

  • IBD
  • genetics
  • genomics
  • translational research
  • metagenomics
  • gut microbiota

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