Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Kate E Mackin; Briony Elliott; Despina Kotsanas; Benjamin P Howden; Glen P Carter; Tony M Korman; Thomas V Riley; Julian I Rood; Grant A Jenkin; Dena Lyras

doi:10.1016/j.anaerobe.2015.05.001

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Kate E Mackin
, Briony Elliott
, Despina Kotsanas
, Benjamin P Howden
, Glen P Carter
, Tony M Korman
, Thomas V Riley
, Julian I Rood
, Grant A Jenkin
, Dena Lyras

Research output: Contribution to journal › Article › Other › peer-review

8 Citations (Scopus)

Abstract

Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains.

Original language	English
Pages (from-to)	80 - 83
Number of pages	4
Journal	Anaerobe
Volume	34
DOIs	https://doi.org/10.1016/j.anaerobe.2015.05.001
Publication status	Published - 2015

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10.1016/j.anaerobe.2015.05.001

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title = "Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia",

abstract = "Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains.",

author = "Mackin, \{Kate E\} and Briony Elliott and Despina Kotsanas and Howden, \{Benjamin P\} and Carter, \{Glen P\} and Korman, \{Tony M\} and Riley, \{Thomas V\} and Rood, \{Julian I\} and Jenkin, \{Grant A\} and Dena Lyras",

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doi = "10.1016/j.anaerobe.2015.05.001",

language = "English",

volume = "34",

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T1 - Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

AU - Mackin, Kate E

AU - Elliott, Briony

AU - Kotsanas, Despina

AU - Howden, Benjamin P

AU - Carter, Glen P

AU - Korman, Tony M

AU - Riley, Thomas V

AU - Rood, Julian I

AU - Jenkin, Grant A

AU - Lyras, Dena

PY - 2015

Y1 - 2015

N2 - Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains.

AB - Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains.

UR - http://www.ncbi.nlm.nih.gov/pubmed/25944720

U2 - 10.1016/j.anaerobe.2015.05.001

DO - 10.1016/j.anaerobe.2015.05.001

M3 - Article

SN - 1075-9964

VL - 34

SP - 80

EP - 83

JO - Anaerobe

JF - Anaerobe

ER -

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Abstract

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Other files and links

The role of Clostridium difficile virulence factors in mediating the host-pathogen interactions that lead to gastrointestinal disease

Molecular characterisation of hypervirulence and the infectious cycle in Clostridium difficile.

Cite this

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Abstract

Access to Document

Other files and links

Projects

The role of Clostridium difficile virulence factors in mediating the host-pathogen interactions that lead to gastrointestinal disease

Molecular characterisation of hypervirulence and the infectious cycle in Clostridium difficile.

Cite this