Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors

Shanshan Ma, Qingya Shen, Li Hua Zhao, Chunyou Mao, X. Edward Zhou, Dan Dan Shen, Parker W. de Waal, Peng Bi, Chuntao Li, Yi Jiang, Ming Wei Wang, Patrick M. Sexton, Denise Wootten, Karsten Melcher, Yan Zhang, H. Eric Xu

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5 Citations (Scopus)

Abstract

The fully active structures of CRF receptors reveal the basis for peptide-binding specificity, support a universal mechanism of class B GPCR activation, and provide detailed structural information for studying membrane protein-lipid interactions.

Original languageEnglish
Pages (from-to)669-680.e4
Number of pages16
JournalMolecular Cell
Volume77
Issue number3
DOIs
Publication statusPublished - 6 Feb 2020

Cite this

Ma, S., Shen, Q., Zhao, L. H., Mao, C., Zhou, X. E., Shen, D. D., de Waal, P. W., Bi, P., Li, C., Jiang, Y., Wang, M. W., Sexton, P. M., Wootten, D., Melcher, K., Zhang, Y., & Xu, H. E. (2020). Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Molecular Cell, 77(3), 669-680.e4. https://doi.org/10.1016/j.molcel.2020.01.013