Molecular analysis of human glomerulonephritis

David J. Nikolic-Paterson, Ian W. Main, Hui Y. Lan, Rita Foti, Robert C. Atkins

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Understanding the complex mechanisms involved in the induction and progression of glomerulonephritis requires a detailed analysis of the disease at the molecular level. This has become possible with the advent of antibody- based, and in particular, DNA-based techologies. This paper provides an overview of the methods of molecular analysis currently in use in the study of human glomerulonephritis. Although largely restricted to the research laboratories at present, these techniques of molecular analysis are now entering the mainstream of clinical diagnostic testing.

Original languageEnglish
Pages (from-to)647-651
Number of pages5
JournalNephrology
Volume3
Issue numberSUPPL. 2
Publication statusPublished - 1 Jan 1997
Externally publishedYes

Keywords

  • CD44
  • Genetic analysis
  • IgA nephropathy
  • Transforming growth factor- β

Cite this

Nikolic-Paterson, D. J., Main, I. W., Lan, H. Y., Foti, R., & Atkins, R. C. (1997). Molecular analysis of human glomerulonephritis. Nephrology, 3(SUPPL. 2), 647-651.