@inbook{cdecdbefd87c4399851ce8aa61f55612,
title = "Modeling acute myeloid leukemia using StarPEG-heparin hydrogels",
abstract = "Biomimetic semi-synthetic hydrogels formed from a combination of star-shaped poly(ethylene glycol) (starPEG) and the glycosaminoglycan, heparin, allows for the three-dimensional (3D) culture of various cells and tissues. In this chapter, we describe methods for the use of starPEG-heparin hydrogels to cultivate primary and immortalized human acute myeloid leukemia (AML) cells. The resulting 3D culture models allow for the study of AML development and response to chemotherapeutic agents.",
keywords = "3D model, Acute myeloid leukemia, Hydrogel",
author = "Holloway, {P. Lewen} and Akhilandeshwari Ravichandran and Julien Clegg and Claudia Bruedigam and Bray, {Laura J.}",
note = "Publisher Copyright: {\textcopyright} 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2024",
doi = "10.1007/978-1-0716-3674-9_6",
language = "English",
isbn = "9781071636732",
volume = "2764",
series = "Methods in Molecular Biology",
publisher = "Springer Science + Business Media",
pages = "61--73",
editor = "{Sumbalova Koledova}, Zuzana",
booktitle = "3D Cell Culture",
}