Mobilisation strategies for normal and malignant cells

L. Bik To, Jean Pierre Levesque, Kirsten E Herbert, Ingrid G Winkler, Linda J. Bendall, Devendra K Hiwase, Vicki Antonenas, Alison M. Rice, david gottlieb, Anthony K. Mills, John EJ Rasko, Stephen Larsen, Ashanka Beligaswatte, Susan K. Nilsson, Julian P. Cooney, Antony C. Cambareri, Ian D. Lewis

Research output: Contribution to journalReview ArticleResearchpeer-review

10 Citations (Scopus)

Abstract

This review evaluates the latest information on the mobilisation of haemopoietic stem cells for transplantation, with the focus on what is the current best practice and how new understanding of the bone marrow stem cell niche provides new insights into optimising mobilisation regimens. The review then looks at the mobilisation of mesenchymal stromal cells, immune cells as well as malignant cells and what clinical implications there are.

Original languageEnglish
Pages (from-to)547-565
Number of pages19
JournalPathology
Volume43
Issue number6
DOIs
Publication statusPublished - Oct 2011
Externally publishedYes

Keywords

  • Haemopoietic stem cells
  • Immune cells
  • Leukaemic cells
  • Mobilisation

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