Mitophagy and mitoptosis in disease processes

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

17 Citations (Scopus)

Abstract

Mitochondria play a very important role in cellular function, not only through key metabolic reactions and energy generation, but also by being a major site for production of reactive oxygen species and a key player in cell death. Therefore, mitochondrial dysfunction or damage may have severe consequences. Mitophagy (autophagic degradation of mitochondria) and mitoptosis (programmed destruction of mitochondria) are the processes by which cells can deal with impaired mitochondria. The efficiency of these processes may be a contributing factor to the pathogenesis of various diseases.
Original languageEnglish
Title of host publicationProtein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols
EditorsPeter Bross, Niels Gregersen
Place of PublicationUK
PublisherHumana Press
Pages93 - 106
Number of pages14
Edition1st
ISBN (Print)9781607617556
DOIs
Publication statusPublished - 2010

Cite this

Mijaljica, D., Prescott, M., & Devenish, R. J. (2010). Mitophagy and mitoptosis in disease processes. In P. Bross, & N. Gregersen (Eds.), Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols (1st ed., pp. 93 - 106). UK: Humana Press. https://doi.org/10.1007/978-1-60761-756-3_6
Mijaljica, Dalibor ; Prescott, Mark ; Devenish, Rodney James. / Mitophagy and mitoptosis in disease processes. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. editor / Peter Bross ; Niels Gregersen. 1st. ed. UK : Humana Press, 2010. pp. 93 - 106
@inbook{429587c821974214be84e1e80039e8aa,
title = "Mitophagy and mitoptosis in disease processes",
abstract = "Mitochondria play a very important role in cellular function, not only through key metabolic reactions and energy generation, but also by being a major site for production of reactive oxygen species and a key player in cell death. Therefore, mitochondrial dysfunction or damage may have severe consequences. Mitophagy (autophagic degradation of mitochondria) and mitoptosis (programmed destruction of mitochondria) are the processes by which cells can deal with impaired mitochondria. The efficiency of these processes may be a contributing factor to the pathogenesis of various diseases.",
author = "Dalibor Mijaljica and Mark Prescott and Devenish, {Rodney James}",
year = "2010",
doi = "10.1007/978-1-60761-756-3_6",
language = "English",
isbn = "9781607617556",
pages = "93 -- 106",
editor = "Peter Bross and Niels Gregersen",
booktitle = "Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols",
publisher = "Humana Press",
address = "United States of America",
edition = "1st",

}

Mijaljica, D, Prescott, M & Devenish, RJ 2010, Mitophagy and mitoptosis in disease processes. in P Bross & N Gregersen (eds), Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. 1st edn, Humana Press, UK, pp. 93 - 106. https://doi.org/10.1007/978-1-60761-756-3_6

Mitophagy and mitoptosis in disease processes. / Mijaljica, Dalibor; Prescott, Mark; Devenish, Rodney James.

Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. ed. / Peter Bross; Niels Gregersen. 1st. ed. UK : Humana Press, 2010. p. 93 - 106.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

TY - CHAP

T1 - Mitophagy and mitoptosis in disease processes

AU - Mijaljica, Dalibor

AU - Prescott, Mark

AU - Devenish, Rodney James

PY - 2010

Y1 - 2010

N2 - Mitochondria play a very important role in cellular function, not only through key metabolic reactions and energy generation, but also by being a major site for production of reactive oxygen species and a key player in cell death. Therefore, mitochondrial dysfunction or damage may have severe consequences. Mitophagy (autophagic degradation of mitochondria) and mitoptosis (programmed destruction of mitochondria) are the processes by which cells can deal with impaired mitochondria. The efficiency of these processes may be a contributing factor to the pathogenesis of various diseases.

AB - Mitochondria play a very important role in cellular function, not only through key metabolic reactions and energy generation, but also by being a major site for production of reactive oxygen species and a key player in cell death. Therefore, mitochondrial dysfunction or damage may have severe consequences. Mitophagy (autophagic degradation of mitochondria) and mitoptosis (programmed destruction of mitochondria) are the processes by which cells can deal with impaired mitochondria. The efficiency of these processes may be a contributing factor to the pathogenesis of various diseases.

UR - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20700707

U2 - 10.1007/978-1-60761-756-3_6

DO - 10.1007/978-1-60761-756-3_6

M3 - Chapter (Book)

SN - 9781607617556

SP - 93

EP - 106

BT - Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols

A2 - Bross, Peter

A2 - Gregersen, Niels

PB - Humana Press

CY - UK

ER -

Mijaljica D, Prescott M, Devenish RJ. Mitophagy and mitoptosis in disease processes. In Bross P, Gregersen N, editors, Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols. 1st ed. UK: Humana Press. 2010. p. 93 - 106 https://doi.org/10.1007/978-1-60761-756-3_6