Mitochondrial biogenesis: cell-cycle-dependent investment in making mitochondria

Takuya Shiota; Ana Traven; Trevor J Lithgow

doi:10.1016/j.cub.2014.12.006

Mitochondrial biogenesis: cell-cycle-dependent investment in making mitochondria

Takuya Shiota, Ana Traven, Trevor J Lithgow

Research output: Contribution to journal › Comment / Debate › Research › peer-review

24 Citations (Scopus)

Abstract

Mitochondria cannot be made de novo, so pre-existing mitochondria must be inherited at each cell division. A new study demonstrates cell-cycle-dependent regulation of the activity of the TOM translocase complex to induce mitochondrial biogenesis during the M phase of the cell cycle.

Original language	English
Pages (from-to)	78 - 80
Number of pages	3
Journal	Current Biology
Volume	25
Issue number	2
DOIs	https://doi.org/10.1016/j.cub.2014.12.006
Publication status	Published - 2015

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title = "Mitochondrial biogenesis: cell-cycle-dependent investment in making mitochondria",

abstract = "Mitochondria cannot be made de novo, so pre-existing mitochondria must be inherited at each cell division. A new study demonstrates cell-cycle-dependent regulation of the activity of the TOM translocase complex to induce mitochondrial biogenesis during the M phase of the cell cycle.",

author = "Takuya Shiota and Ana Traven and Lithgow, {Trevor J}",

year = "2015",

doi = "10.1016/j.cub.2014.12.006",

language = "English",

volume = "25",

pages = "78 -- 80",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "2",

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TY - JOUR

T1 - Mitochondrial biogenesis: cell-cycle-dependent investment in making mitochondria

AU - Shiota, Takuya

AU - Traven, Ana

AU - Lithgow, Trevor J

PY - 2015

Y1 - 2015

N2 - Mitochondria cannot be made de novo, so pre-existing mitochondria must be inherited at each cell division. A new study demonstrates cell-cycle-dependent regulation of the activity of the TOM translocase complex to induce mitochondrial biogenesis during the M phase of the cell cycle.

AB - Mitochondria cannot be made de novo, so pre-existing mitochondria must be inherited at each cell division. A new study demonstrates cell-cycle-dependent regulation of the activity of the TOM translocase complex to induce mitochondrial biogenesis during the M phase of the cell cycle.

UR - http://www.sciencedirect.com/science/article/pii/S096098221401567X

U2 - 10.1016/j.cub.2014.12.006

DO - 10.1016/j.cub.2014.12.006

M3 - Comment / Debate

SN - 0960-9822

VL - 25

SP - 78

EP - 80

JO - Current Biology

JF - Current Biology

IS - 2

ER -

Mitochondrial biogenesis: cell-cycle-dependent investment in making mitochondria

Abstract

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