TY - JOUR
T1 - MicroRNAs in Tfh cells: micromanaging inflammaging
AU - Yu, Di
PY - 2014
Y1 - 2014
N2 - MicroRNA (miR)-146a-deficient mice develop low-grade, chronic, and systemic inflammation, similar to inflammaging. Hu et al. (2014) demonstrate that the lack of miR-155 prevents the accumulation of Tfh cells and inflammaging in miR-146a-deficient mice. They identify Fosl2 as a functionally important target of miR-155 in Tfh cells.
AB - MicroRNA (miR)-146a-deficient mice develop low-grade, chronic, and systemic inflammation, similar to inflammaging. Hu et al. (2014) demonstrate that the lack of miR-155 prevents the accumulation of Tfh cells and inflammaging in miR-146a-deficient mice. They identify Fosl2 as a functionally important target of miR-155 in Tfh cells.
UR - http://www.sciencedirect.com/science/article/pii/S1074761314003598
U2 - 10.1016/j.immuni.2014.10.003
DO - 10.1016/j.immuni.2014.10.003
M3 - Short Survey
SN - 1074-7613
VL - 41
SP - 509
EP - 511
JO - Immunity
JF - Immunity
IS - 4
ER -