Abstract
Adult bronchiectasis is a significant cause of respiratory illness. A systematic review of the microbiologie flora of adult bronchiectasis in Australia has not been done previously. AIM: To characterise the type of bacteria in the sputum of patients who present with an exacerbation of bronchiectasis. METHODS: Sputum samples were collected from a cohort of 100 patients. Standard microscopy, culture and sensitivity were performed; and 30 of the samples were processed for the presence of mycobacteria. Sensitivities for first line antibiotics listed: A=ampicillin, P=penicillin, F=flucloxacillin, G=gentamicin. Isolates were considered significant when there were at least 2+ polymorphs on gram stain with at least moderate growth on culture. RESULTS: 67 of the 100 patients produced a significant isolate. 14% of the cultures produced 2 or more significant isolates Bacteria % Frequency Sensitivity H. influenzae 45% 87% (A) S.pneumoniae 15% 90% (P) S. aureus 14% 78% (F) M. catarrhalis 8% 40% (A) Pseudomonas species 24% 69% (G) Other Gram-ve species 11% 71% (G) Mycobacteria 1% 100% CONCLUSION: This cohort had a wide variety of different bacteria isolated. The presence of Pseudomonas and resistant gram-negative bacteria was strongly associated with hospitalization.
Original language | English |
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Journal | Respirology |
Volume | 6 |
Issue number | SUPPL. 1 |
Publication status | Published - 1 Dec 2001 |
Keywords
- Bronchiectasis
- H influenzae
- Sensitivity
- Sputum