Micelle formation of amphiphilic polystyrene-b-poly(N-vinylpyrrolidone) diblock copolymer in methanol and water-methanol binary mixtures

Hazrat Hussain, B. H. Tan, Chakravarthy S Gudipati, C B He, Y Liu, Thomas P Davis

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)


The micelle formation by the amphiphilic polystyrene-block-poly(N- vinylpyrrolidone) (PS48-b-PNVP99) copolymer is investigated in methanol and water-methanol binary mixtures of various compositions using 1H NMR, fluorescence spectroscopy, static/dynamic light scattering (SLS/DLS), and transmission electron microscopy (TEM). Critical micelle concentrations (cmc) are determined by employing fluorescence spectroscopy and DLS measurements. The cmc of the PS48-b-PNVP 99 block copolymer increases with increasing methanol content in the water-methanol binary mixtures, suggesting that methanol is a better solvent for the PS48-b-PNVP99 block copolymer than water-methanol mixtures or pure water. The amphiphilic PS48-b-PNVP99 diblock copolymer forms spherical micelles of Rh ∼ 16 nm in pure methanol solution as revealed by DLS measurements. In contrast, significantly larger micelles having higher aggregation numbers are formed in water-methanol binary mixtures. Temperature dependent data reveal an increase in aggregation number and radius of gyration (Rg) concomitantly with temperature (10-40°C). In contrast, the overall size (Rh) of the micelles remains almost constant over the same temperature range. An explanation is tendered that PNVP coronas dehydrate/desolvate at higher temperatures counteracting the increase in micelle size (Rh) caused by increased aggregation numbers (Nagg). 

Original languageEnglish
Pages (from-to)5557-5564
Number of pages8
Issue number10
Publication statusPublished - 19 May 2009
Externally publishedYes

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