Methylprednisolone applied directly to the round window reduces dizziness after cochlear implantation: A randomized clinical trial

Joanne Enticott, Hayden Eastwood, Robert Briggs, Richard Dowell, Stephen O'Leary

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Abstract

This prospective, double-blind controlled, randomized clinical trial of 43 adults showed that topical methylprednisolone applied to the round window during cochlear implantation was effective in protecting inner ear function. Postoperative vestibular disturbance was significantly lower in the steroid group (5 ) than the control group (29 ). Electrode impedances from the middle portion of the electrode array (electrodes 10a??13) were significantly reduced in steroidtreated recipients compared to controls. Hearing and vestibular function analyses were under-powered to detect any drug changes due to limited participant data.
Original languageEnglish
Pages (from-to)289 - 303
Number of pages15
JournalAudiology and Neurotology
Volume16
Issue number5
DOIs
Publication statusPublished - 2011
Externally publishedYes

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