Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 655 - 664 |
| Number of pages | 10 |
| Journal | Journal of Child and Adolescent Psychopharmacology |
| Volume | 23 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2013 |
Cite this
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Methylphenidate side effect profile is influenced by genetic variation in the attention-deficit/hyperactivity disorder-associated CES1 gene. / Johnson, Katherine A; Barry, Edwina; Lambert, David; Fitzgerald, Michael F; McNicholas, Fiona; Kirley, Aiveen; Gill, Michael; Bellgrove, Mark Andrew; Hawi, Ziarih.
In: Journal of Child and Adolescent Psychopharmacology, Vol. 23, No. 10, 2013, p. 655 - 664.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Methylphenidate side effect profile is influenced by genetic variation in the attention-deficit/hyperactivity disorder-associated CES1 gene
AU - Johnson, Katherine A
AU - Barry, Edwina
AU - Lambert, David
AU - Fitzgerald, Michael F
AU - McNicholas, Fiona
AU - Kirley, Aiveen
AU - Gill, Michael
AU - Bellgrove, Mark Andrew
AU - Hawi, Ziarih
PY - 2013
Y1 - 2013
N2 - A naturalistic, prospective study of the influence of genetic variation on dose prescribed, clinical response, and side effects related to stimulant medication in 77 children with attention-deficit/hyperactivity disorder (ADHD) was undertaken. The influence of genetic variation of the CES1 gene coding for carboxylesterase 1A1 (CES1A1), the major enzyme responsible for the first-pass, stereoselective metabolism of methylphenidate, was investigated.
AB - A naturalistic, prospective study of the influence of genetic variation on dose prescribed, clinical response, and side effects related to stimulant medication in 77 children with attention-deficit/hyperactivity disorder (ADHD) was undertaken. The influence of genetic variation of the CES1 gene coding for carboxylesterase 1A1 (CES1A1), the major enzyme responsible for the first-pass, stereoselective metabolism of methylphenidate, was investigated.
UR - http://online.liebertpub.com/doi/pdf/10.1089/cap.2013.0032
U2 - 10.1089/cap.2013.0032
DO - 10.1089/cap.2013.0032
M3 - Article
VL - 23
SP - 655
EP - 664
JO - Journal of Child and Adolescent Psychopharmacology
JF - Journal of Child and Adolescent Psychopharmacology
SN - 1044-5463
IS - 10
ER -