TY - JOUR
T1 - Methods for living guidelines
T2 - early guidance based on practical experience. Article 5: decisions on methods for evidence synthesis and recommendation development for living guidelines
AU - Fraile Navarro, David
AU - Cheyne, Saskia
AU - Hill, Kelvin
AU - McFarlane, Emma
AU - Morgan, Rebecca L.
AU - Murad, M. Hassan
AU - Mustafa, Reem A.
AU - Sultan, Shahnaz
AU - Tunnicliffe, David J.
AU - Vogel, Joshua P.
AU - White, Heath
AU - Turner, Tari
N1 - Funding Information:
This article was not funded. The National COVID-19 Clinical Evidence Taskforce is supported by: Australian Government Department of Health, Victorian Government Department of Health and Human Services, The Ian Potter Foundation, Walter Cottman Endowment Fund (managed by Equity Trustees), Lord Mayors’ Charitable Foundation. The Australian Evidence-Based Clinical Guidelines for Diabetes is supported by: Australian Diabetes Society, Diabetes Australia, Australian Diabetes Educators Association, Australasian Paediatric Endocrine Group and the Australian Government Department of Health. The Australian Living Guideline for the Pharmacological Management of Inflammatory Arthritis is supported by the Australian Government’s Value in Prescribing program grant, managed by the Targeted Therapies Alliance, a consortium coordinated by NPS MedicineWise.NICE receives funding from the Department of Health and Social Care in England.Work to complete the systematic reviews which informed the IDSA COVID-19 guidelines was primary funded by the IDSA with contribution from the Evidence Foundation.
Publisher Copyright:
© 2023 Elsevier Inc.
PY - 2023/3
Y1 - 2023/3
N2 - Objectives: Producing living guidelines requires making important decisions about methods for evidence identification, appraisal, and integration to allow the living mode to function. Clarifying what these decisions are and the trade-offs between options is necessary. This article provides living guideline developers with a framework to enable them to choose the most suitable model for their living guideline topic, question, or context. Study Design and Setting: We developed this guidance through an iterative process informed by interviews, feedback, and a consensus process with an international group of living guideline developers. Results: Several key decisions need to be made both before commencing and throughout the continual process of living guideline development and maintenance. These include deciding what approach is taken to the systematic review process; decisions about methods to be applied for the evidence appraisal process, including the use of unpublished data; and selection of “triggers” to incorporate new studies into living guideline recommendations. In each case, there are multiple options and trade-offs. Conclusion: We identify trade-offs and important decisions to be considered throughout the living guideline development process. The most appropriate, and most sustainable, mode of development and updating will be dependent on the choices made in each of these areas.
AB - Objectives: Producing living guidelines requires making important decisions about methods for evidence identification, appraisal, and integration to allow the living mode to function. Clarifying what these decisions are and the trade-offs between options is necessary. This article provides living guideline developers with a framework to enable them to choose the most suitable model for their living guideline topic, question, or context. Study Design and Setting: We developed this guidance through an iterative process informed by interviews, feedback, and a consensus process with an international group of living guideline developers. Results: Several key decisions need to be made both before commencing and throughout the continual process of living guideline development and maintenance. These include deciding what approach is taken to the systematic review process; decisions about methods to be applied for the evidence appraisal process, including the use of unpublished data; and selection of “triggers” to incorporate new studies into living guideline recommendations. In each case, there are multiple options and trade-offs. Conclusion: We identify trade-offs and important decisions to be considered throughout the living guideline development process. The most appropriate, and most sustainable, mode of development and updating will be dependent on the choices made in each of these areas.
KW - Clinical practice guidelines
KW - Evidence-based medicine
KW - Living evidence
KW - Living guidelines
KW - Methods
KW - Systematic reviews
UR - http://www.scopus.com/inward/record.url?scp=85147128568&partnerID=8YFLogxK
U2 - 10.1016/j.jclinepi.2022.12.022
DO - 10.1016/j.jclinepi.2022.12.022
M3 - Article
C2 - 36608720
AN - SCOPUS:85147128568
SN - 0895-4356
SP - 118
EP - 128
JO - Journal of Clinical Epidemiology
JF - Journal of Clinical Epidemiology
ER -