Metallochaperone-like genes in Arabidopsis thaliana

Muhammad Tehseen, Narelle Cairns, Sarah Sherson, Christopher Cobbett

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Abstract

A complete inventory of metallochaperone-like proteins containing a predicted HMA domain in Arabidopsis revealed a large family of 67 proteins. 45 proteins, the HIPPs, have a predicted isoprenylation site while 22 proteins, the HPPs, do not. Sequence comparisons divided the proteins into seven major clusters (I-VII). Cluster IV is notable for the presence of a conserved Asp residue before the CysXXCys, metal binding motif, analogous to the Zn binding motif in E. coil ZntA. HIPP20, HIPP21, HIPP22. HIPP26 and HIPP27 in Cluster IV were studied in more detail.
Original languageEnglish
Pages (from-to)556 - 564
Number of pages9
JournalMetallomics
Volume2
Issue number8
DOIs
Publication statusPublished - 2010
Externally publishedYes

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