Membrane proteomics: The development of diagnostics based on protein shedding

Zon Weng Lai, David Lawrence Steer, Alexander Ian Smith

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Advances in proteomics technologies, in particular the parallel development of highly sensitive mass spectrometeres and accurate protein quantitation technologies, have allowedthe detection and accurate measurement of low abundance proteins in bodily fluids and tissues. Furthermore, the application of these technologies in biomedical research has led to the identification of proteins and genes with expression pattenrs that change as a consequence of disease;......
Original languageEnglish
Pages (from-to)623 - 631
Number of pages9
JournalCurrent Opinion in Molecular Therapeutics
Volume11
Issue number6
Publication statusPublished - 2009

Cite this

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title = "Membrane proteomics: The development of diagnostics based on protein shedding",
abstract = "Advances in proteomics technologies, in particular the parallel development of highly sensitive mass spectrometeres and accurate protein quantitation technologies, have allowedthe detection and accurate measurement of low abundance proteins in bodily fluids and tissues. Furthermore, the application of these technologies in biomedical research has led to the identification of proteins and genes with expression pattenrs that change as a consequence of disease;......",
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year = "2009",
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pages = "623 -- 631",
journal = "Current Opinion in Molecular Therapeutics",
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}

Membrane proteomics: The development of diagnostics based on protein shedding. / Lai, Zon Weng; Steer, David Lawrence; Smith, Alexander Ian.

In: Current Opinion in Molecular Therapeutics, Vol. 11, No. 6, 2009, p. 623 - 631.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Membrane proteomics: The development of diagnostics based on protein shedding

AU - Lai, Zon Weng

AU - Steer, David Lawrence

AU - Smith, Alexander Ian

PY - 2009

Y1 - 2009

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AB - Advances in proteomics technologies, in particular the parallel development of highly sensitive mass spectrometeres and accurate protein quantitation technologies, have allowedthe detection and accurate measurement of low abundance proteins in bodily fluids and tissues. Furthermore, the application of these technologies in biomedical research has led to the identification of proteins and genes with expression pattenrs that change as a consequence of disease;......

UR - http://www.ncbi.nlm.nih.gov/pubmed/20072939?dopt=Abstract

M3 - Article

VL - 11

SP - 623

EP - 631

JO - Current Opinion in Molecular Therapeutics

JF - Current Opinion in Molecular Therapeutics

SN - 1464-8431

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ER -