Membrane proteomics: The development of diagnostics based on protein shedding

Zon Weng Lai, David Lawrence Steer, Alexander Ian Smith

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Abstract

Advances in proteomics technologies, in particular the parallel development of highly sensitive mass spectrometeres and accurate protein quantitation technologies, have allowedthe detection and accurate measurement of low abundance proteins in bodily fluids and tissues. Furthermore, the application of these technologies in biomedical research has led to the identification of proteins and genes with expression pattenrs that change as a consequence of disease;......
Original languageEnglish
Pages (from-to)623 - 631
Number of pages9
JournalCurrent Opinion in Molecular Therapeutics
Volume11
Issue number6
Publication statusPublished - 2009

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