Mechanisms of upper limb amyotrophy in spinal disorders

Emma Foster, Benjamin K T Tsang, Anthony Kam, Richard J Stark

Research output: Contribution to journalArticleOther

15 Citations (Scopus)


Upper limb amyotrophy may occur as an indirect consequence of various spinal disorders, including ventral longitudinal intraspinal fluid collection, Hirayama disease and high cervical cord compression. We present patients who suffer from each of these and review the literature on the three conditions with emphasis on the pathogenesis of amyotrophy. We propose that pathology some distance from the lower cervical spinal cord may affect normal venous drainage, resulting in venous congestion and reduced perfusion pressure which, in turn, could result in anterior horn cell dysfunction in all three disorders.
Original languageEnglish
Pages (from-to)1209 - 1214
Number of pages6
JournalJournal of Clinical Neuroscience
Issue number7
Publication statusPublished - 2014

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