Mechanisms of abnormal gene expression in tumor cells.

Assam El-Osta

Mechanisms of abnormal gene expression in tumor cells.

Assam El-Osta

Research output: Contribution to journal › Review Article › Research › peer-review

Abstract

Epigenetic mechanisms are involved in critical nuclear processes such as transcriptional control, genome stability, replication and repair. Recent evidence suggests that changes in the epigenetic repertoire can drive tumorigenesis. This review examines the latest experimental evidence that questions the mechanisms underlying the consequence of epigenetic changes in gene regulation and cancer development.

Original language	English
Pages (from-to)	351-361
Number of pages	11
Journal	EXS
Issue number	96
Publication status	Published - 1 Jan 2006
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

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title = "Mechanisms of abnormal gene expression in tumor cells.",

abstract = "Epigenetic mechanisms are involved in critical nuclear processes such as transcriptional control, genome stability, replication and repair. Recent evidence suggests that changes in the epigenetic repertoire can drive tumorigenesis. This review examines the latest experimental evidence that questions the mechanisms underlying the consequence of epigenetic changes in gene regulation and cancer development.",

author = "Assam El-Osta",

year = "2006",

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language = "English",

pages = "351--361",

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N2 - Epigenetic mechanisms are involved in critical nuclear processes such as transcriptional control, genome stability, replication and repair. Recent evidence suggests that changes in the epigenetic repertoire can drive tumorigenesis. This review examines the latest experimental evidence that questions the mechanisms underlying the consequence of epigenetic changes in gene regulation and cancer development.

AB - Epigenetic mechanisms are involved in critical nuclear processes such as transcriptional control, genome stability, replication and repair. Recent evidence suggests that changes in the epigenetic repertoire can drive tumorigenesis. This review examines the latest experimental evidence that questions the mechanisms underlying the consequence of epigenetic changes in gene regulation and cancer development.

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M3 - Review Article

C2 - 16383026

AN - SCOPUS:33644839745

SN - 1023-294X

SP - 351

EP - 361

JO - EXS

JF - EXS

IS - 96

ER -

Mechanisms of abnormal gene expression in tumor cells.

Abstract

UN SDGs

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