Abstract
The replacement of current generation HFA propellants with low global warming potential (GWP) alternatives such as HFA152a and HFO1234ze(E) in solution based pressurized metered-dose inhaler (pMDIs) is not straightforward due to a lack of thermophysical property data for binary mixtures of low GWP propellants with ethanol [1, 2]. Changes in vapor pressure, density, viscosity, and surface tension can influence the atomization mechanics of pMDI sprays [3–5]. In this study the vapor pressure and viscosity of ethanol with HFA134a, HFA152a, and HFO1234ze(E) were measured with ethanol concentrations varying from 4% w/w to 90% w/w for completeness of the property data.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of Respiratory Drug Delivery 2024 |
| Editors | Dalby RN, Peart J, Suman JD, Young PM, Traini D, Watts A |
| Publisher | RDD Online |
| Pages | 346-350 |
| Number of pages | 5 |
| ISBN (Electronic) | 9781739682125 |
| Publication status | Published - 2024 |
| Event | Respiratory Drug Delivery 2024 - Tuscon, United States of America Duration: 5 May 2024 → 9 May 2024 https://www.rddonline.com/rdd/rdd.php?id=23&sid=1 |
Conference
| Conference | Respiratory Drug Delivery 2024 |
|---|---|
| Abbreviated title | RDD 2023 |
| Country/Territory | United States of America |
| City | Tuscon |
| Period | 5/05/24 → 9/05/24 |
| Internet address |