TY - JOUR
T1 - Means and variances in stochastic multistage cancer models
AU - Sudbury, Aidan Waverley
PY - 2012
Y1 - 2012
N2 - A widely used model of carcinogenesis assumes that cells must go through a process of acquiring several mutations before they become cancerous. This implies that at any time there will be several populations of cells at different stages of mutation. In this paper we give exact expressions for the expectations and variances of the number of cells in each stage of such a stochastic multistage cancer model.
AB - A widely used model of carcinogenesis assumes that cells must go through a process of acquiring several mutations before they become cancerous. This implies that at any time there will be several populations of cells at different stages of mutation. In this paper we give exact expressions for the expectations and variances of the number of cells in each stage of such a stochastic multistage cancer model.
UR - http://projecteuclid.org/DPubS?service=UI&version=1.0&verb=Display&handle=euclid.jap/1339878807
U2 - 10.1239/jap/1339878807
DO - 10.1239/jap/1339878807
M3 - Article
SN - 0021-9002
VL - 49
SP - 590
EP - 594
JO - Journal of Applied Probability
JF - Journal of Applied Probability
IS - 2
ER -
