@article{c7be0ce9fe724999b22868598d52a6cf,
title = "Mathematical performance in childhood and early adult outcomes after very preterm birth: an individual participant data meta-analysis",
abstract = "Aim: To investigate the strength of the independent associations of mathematics performance in children born very preterm (<32wks' gestation or <1500g birthweight) with attending postsecondary education and their current employment status in young adulthood. Method: We harmonized data from six very preterm birth cohorts from five different countries and carried out one-stage individual participant data meta-analyses (n=954, 52% female) using mixed effects logistic regression models. Mathematics scores at 8 to 11 years of age were z-standardized using contemporary cohort-specific controls. Outcomes included any postsecondary education, and employment/education status in young adulthood. All models were adjusted for year of birth, gestational age, sex, maternal education, and IQ in childhood. Results: Higher mathematics performance in childhood was independently associated with having attended any postsecondary education (odds ratio [OR] per SD increase in mathematics z-score: 1.36 [95% confidence interval {CI}: 1.03, 1.79]) but not with current employment/education status (OR 1.14 per SD increase [95% CI: 0.87, 1.48]). Interpretation: Among populations born very preterm, childhood mathematics performance is important for adult educational attainment, but not for employment status.",
author = "Julia Jaekel and Anderson, {Peter J.} and Peter Bartmann and Cheong, {Jeanie L.Y.} and Doyle, {Lex W.} and Maureen Hack and Samantha Johnson and Neil Marlow and Saroj Saigal and Louis Schmidt and Sullivan, {Mary C.} and Dieter Wolke",
note = "Funding Information: We would like to sincerely thank the APIC community for their feedback on the initial data harmonization and analysis strategy. Special thanks are due to Prof Eero Kajantie and Dr Petteri Hovi for allowing access to the Cleveland Study data set after Prof Maureen Hack's passing, and for sharing their harmonization documentation and legal agreement templates. JJ was supported by grant JA 1913/2‐2 from the German Research Foundation. DW and PB were supported by an EU Horizon 2020 grant 733280 (RECAP‐preterm) and DW by the New Opportunities for Research Funding Agency Co‐operation in Europe, Dynamics of Inequality Across the Life‐course Program (grant number: 462‐16‐040). The EPICure studies were funded by the Medical Research Council (MR/N024869/1). NM receives funding from the NIHR Biomedical Research Centre at University College London/University College London Hospitals. The McMaster Study was supported by grant No. ESPM85‐201, Hospital for Sick Children Foundation, Toronto, Ontario and a Team Grant (2009H00529) from the Canadian Institutes of Health Research awarded to LS and SS. The Rhode Island cohort studies were funded by the National Institutes of Health, National Institute of Nursing Research (Grant # R01 NR 003695‐01; R01 NR003695‐14). PA was supported by the Australian National Health and Medical Research Council Investigator Grant (#1176077). JC was supported by Australian Medical Research Future Fund Career Development Fellowship (#1141354). The Victorian Infant Collaborative Study studies were funded by the Australian NHMRC (#1104300, #491246). Publisher Copyright: {\textcopyright} 2021 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press.",
year = "2022",
month = apr,
doi = "10.1111/dmcn.15132",
language = "English",
volume = "64",
pages = "421--428",
journal = "Developmental Medicine & Child Neurology",
issn = "0012-1622",
publisher = "Wiley-Blackwell",
number = "4",
}