Maternal serum inhibin-A in pregnancies complicated by insulin dependent diabetes mellitus

Euan M. Wallace; Jennifer A. Crossley; Savitri C. Ritoe; Nigel P. Groome; David A. Aitken

doi:10.1111/j.1471-0528.1997.tb14356.x

Maternal serum inhibin-A in pregnancies complicated by insulin dependent diabetes mellitus

Euan M. Wallace, Jennifer A. Crossley, Savitri C. Ritoe, Nigel P. Groome, David A. Aitken

Obstetrics & Gynaecology Monash Health

Research output: Contribution to journal › Article › Research › peer-review

20 Citations (Scopus)

Abstract

We have examined whether insulin dependant diabetes mellitus (IDDM) affects maternal serum levels of inhibin-A, a recently described prenatal marker of Down's syndrome, by comparing levels in 169 women with IDDM with levels in 432 nondiabetic pregnant women between 15 and 20 weeks of gestation. There was a small but significant increase in the inhibin-A level in the diabetic women only when levels were corrected for maternal weight: median MoM 1.17 (P < 0.01 vs controls, Student’s t test). The underlying mechanism for this elevation in pregnancies complicated by IDDM currently remains obscure.

Original language	English
Pages (from-to)	946-948
Number of pages	3
Journal	British Journal of Obstetrics and Gynaecology
Volume	104
Issue number	8
DOIs	https://doi.org/10.1111/j.1471-0528.1997.tb14356.x
Publication status	Published - Aug 1997

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AU - Groome, Nigel P.

AU - Aitken, David A.

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Maternal serum inhibin-A in pregnancies complicated by insulin dependent diabetes mellitus

Abstract

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