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Mass effect and signal intensity alteration in the suprapatellar fat pad: associations with knee symptoms and structure

  • J Wang
  • , Weiyu Han
  • , Xia Wang
  • , Faming Pan
  • , Zhenhua Liu
  • , Andrew Halliday
  • , Xingzhong Jin
  • , Benny Antony
  • , Flavia Maria Cicuttini
  • , Graeme Jones
  • , Changhai Ding

Research output: Contribution to journalArticleResearchpeer-review

Abstract

To describe cross-sectional associations between mass effect or signal intensity alteration of the suprapatellar fat pad (SPFP) with knee symptoms and structure in older adults. Methods: A cross-sectional sample of 904 randomly selected subjects (mean 62.4 years, 49.9 female) was studied. T1- or T2-weighted fat suppressed magnetic resonance imaging (MRI) was used to assess mass effect or signal intensity alteration of SPFP, cartilage volume, cartilage defects, and bone marrow lesions (BMLs). Knee pain was assessed by self-administered Western Ontario McMaster Osteoarthritis Index (WOMAC) questionnaire. The Osteoarthritis Research Society International (OARSI) atlas was used to assess knee osteophyte, joint space narrowing (JSN) and radiographic osteoarthritis (ROA). Univariable and multivariable linear or logistic regression analyses were used to examine the associations.
Original languageEnglish
Pages (from-to)1619 - 1626
Number of pages8
JournalOsteoarthritis and Cartilage
Volume22
Issue number10
DOIs
Publication statusPublished - 2014

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