Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis

G. O. Littlejohn, H. A. Smythe

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The insulin response after a glucose challenge was studied in 11 male patients with diffuse idiopathic skeletal hyperostosis (DISH) and in 8 age, sex and weight matched controls. There was significant hyperinsulinemia in the DISH group, most marked at 2 h after the glucose challenge. Growth hormone levels were found to be normal in each group. The marked hyperinsulinemia in patients with DISH may play a role in the pathogenesis of this condition.

Original languageEnglish
Pages (from-to)965-968
Number of pages4
JournalThe Journal of Rheumatology
Issue number6
Publication statusPublished - 1 Dec 1981

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