Many faces of graft-versus-host disease

Pablo F. Peñas, Sarah Zaman

Research output: Contribution to journalReview ArticleResearchpeer-review

30 Citations (Scopus)

Abstract

Allogeneic haematopoietic stem cell transplantation is increasingly used in the treatment of malignant and non-malignant disorders. Despite ongoing advances in the field, morbidity and mortality related to graft-versus-host disease remains a major barrier to its application. Graft-versus-host disease is a difficult-to-diagnose disease. Dermatologists are involved due to its diverse cutaneous expression. In order to appropriately diagnose, classify and treat this complex disease, knowledge of its expanding cutaneous expression is required. This review provides a synopsis of the clinical manifestations of acute, lichenoid and sclerodermatous phases of graft-versus-host disease with a look at the current evidence surrounding its differential diagnosis.

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalAustralasian Journal of Dermatology
Volume51
Issue number1
DOIs
Publication statusPublished - 1 Feb 2010
Externally publishedYes

Keywords

  • Acute graft versus host disease
  • Bone marrow transplant
  • Chronic graft-versus-host disease
  • Cutaneous graft-versus-host disease
  • Graft-versus-host disease
  • Haematopoietic stem cell transplantation
  • Lichenoid
  • Sclerodermatous

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